Terms & Properties

Preferred Name:  Aspirin

Definition:  An orally administered non-steroidal antiinflammatory agent. Acetylsalicylic acid binds to and acetylates serine residues in cyclooxygenases, resulting in decreased synthesis of prostaglandin, platelet aggregation, and inflammation. This agent exhibits analgesic, antipyretic, and anticoagulant properties.

NCI-GLOSS Definition:  A drug that reduces pain, fever, inflammation, and blood clotting. Aspirin belongs to the family of drugs called nonsteroidal anti-inflammatory agents. It is also being studied in cancer prevention.

Display Name:  Aspirin

Label:  Aspirin

NCI Thesaurus Code:  C287 (Search for linked caDSR metadata)   (search value sets)

NCI Metathesaurus Link:  C0004057  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

2-(Acetyloxy)benzoic Acid

Acetylsalicylic acid

Acetylsalicylic Acid

ASA

Aspergum

Aspirin

aspirin

ASPIRIN

Ecotrin

Empirin

Entericin

Extren

Measurin

External Source Codes: 

CAS Registry Number	50-78-2 (see NLM ChemIDplus info)
FDA UNII Code	R16CO5Y76E
ChEBI ID	CHEBI:15365 (see ChEBI info)
PDQ Closed Trial Search ID	39152
PDQ Open Trial Search ID	39152 (check for NCI PDQ open clinical trial info)
UMLS CUI	C0004057

Other Properties:

Name	Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For	Mild to moderate pain; fever; prevention of arterial and venous thrombosis
Chemical_Formula	C9H8O4
code	C287
Contributing_Source	CTRP
Contributing_Source	FDA
Legacy Concept Name	Acetylsalicylic_Acid
NSC Number	406186
Semantic_Type	Organic Chemical
Semantic_Type	Pharmacologic Substance

Additional Concept Data: 

Defined Fully by Roles: No

URL:https://ncit-stage.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C287